pCMV-Tag/M1 N184X vector

Contributors

Institute
Drexel University
SKU: 154332
Product description: Plasmids for the study of hereditary spastic paraplegia
Additional notes: Plasmids for the study of hereditary spastic paraplegia
Cat. #: 154332
Tool sub type: pCMV-Tag
Research Fields: Cell biology; Genetics; Neurobiology
Target: spastin
Backbone size without insert: 4300
Bacterial resistance: Kanamycin
References:

Solowska et al. 2017. Mol Biol Cell. 28(13):1728-1737. PMID: 28495799.

Truncating mutations of SPAST associated with hereditary spastic paraplegia indicate greater accumulation and toxicity of the M1 isoform of spastin.

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