Long chain polyphosphate small molecule (tool compound)

The long chain polyphosphate is linear polymers of inorganic orthophosphate linked by high-energy phosphoanhydride bonds that has an approximate polymer length ranging from 200-1,300 phosphate units. Polyphosphates are secreted from platelets to regulate blood clotting and have been used in plasma clotting assays and to study bacteria growth and function.

Contributors

Inventor Institute
James Morrissey University of Michigan
Product description: The long chain polyphosphate is linear polymers of inorganic orthophosphate linked by high-energy phosphoanhydride bonds that has an approximate polymer length ranging from 200-1,300 phosphate units. Polyphosphates are secreted from platelets to regulate blood clotting and have been used in plasma clotting assays and to study bacteria growth and function.
References:

Wang et al. 2019. J Thromb Haemost. :. PMID: 31420909.

Zilberman-Rudenko et al. 2018. Arterioscler Thromb Vasc Biol. 38(8):1748-1760. PMID: 30354195.

Wijeyewickrema et al. 2016. Blood. 128(13):1766-76. PMID: 27338096.

Choi et al. 2015. Thromb Haemost. 113(3):599-604. PMID: 25338662.

Puy et al. 2013. J Thromb Haemost. 11(7):1341-52. PMID: 23659638.

Smith et al. 2012. Blood. 120(26):5103-10. PMID: 22968458.

Choi et al. 2011. Blood. 118(26):6963-70. PMID: 21976677.

Smith et al. 2010. Blood. 116(20):4353-9. PMID: 20709905.

Choi et al. 2010. Biochemistry. 49(45):9935-41. PMID: 20957999.

Related Tools for Small molecules

Cat. # Tool Name
151880 AKR1C3 inhibitor CRT0093964 Small Molecule (Tool Compound) Key Info View Tool
152754 CDK2 inhibitor NU6301 Small Molecule (Tool Compound) Key Info View Tool
152785 Mitochondrial Luminophore Small Molecule (Tool Compound) Key Info View Tool
152788 Phosphatidylinositol-4-phosphate 5-kinase inhibitor PIP5K Small Molecule (Collaborative Toolkit) Key Info View Tool
153191 CDK inhibitor BS-194 Small Molecule (Tool Compound) Key Info View Tool

Tool enquiry

Please ensure you use your organisation email address rather than personal where possible, as this helps us locate your organisation in our system faster.

Please note we may take up to three days to respond to your enquiry.

CancerTools.org uses the contact information provided to respond to you about our research tools and service. For more information please review our privacy policy.