Deymelination restricted to CNS & lack of remyelination.
| Inventor | Institute |
|---|---|
| Ben Emery | Oregon Health & Science University |
| SKU: | 157783 |
|---|---|
| Product description: | Deymelination restricted to CNS & lack of remyelination. |
| Conditional: | Yes |
| Conditional description: | inducible demyelination without remyelination |
| Cat. #: | 157783 |
|---|---|
| Research Fields: | Neurobiology |
| Target: | Myrf (myelin regulatory factor) |
| Disease: | Tamoxifen activated inactivation of Myrf for demyelination of throughout the CNS |
| Model: | Conditional KO |
| Strain: | C57BL/6 |
| Phenotype: | Demyelination of CNS |
| Shipping conditions: | Embryo/Spermatoza- Dry Ice |
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| References: |
30996143 19596243 McKenzie et al. 2014. Science. 346(6207):318-22. PMID: 25324381. Koenning et al. 2012. J Neurosci. 32(36):12528-42. PMID: 22956843. |
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