p110beta PI3K-floxed

Contributors

Inventor Institute
Bart Vanhaesebroeck Ludwig Institute for Cancer Research ; The University of Edinburgh
SKU: 158394
Conditional: Yes
Genetic background: Exons 21 and 22 of the PIK3CA/p110b PI3K gene are flanked by LoxP sites – backcrossed onto C57B6/J background.
Production details: Exons 21 and 22 of the PIK3CA/p110b PI3K gene are flanked by LoxP sites – backcrossed onto C57B6/J background.
Additional notes: Homozygous and heterozygous mice are phenotypically normal.
Cat. #: 158394
Research Fields: Cancer
Target: PIK3CB
Model: Conditional KO
Phenotype: Homozygous and heterozygous mice are phenotypically normal.
Shipping conditions: Embryo/Spermatoza- Dry Ice
References:

Kulkarni et al. 2011. Sci Signal. 4(168):ra23. PMID: 21487106.

Guillermet-Guibert et al. 2008. Proc Natl Acad Sci U S A. 105(24):8292-7. PMID: 18544649.

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