p110beta PI3K-DEL21/22 (B6)

Contributors

Inventor Institute
Bart Vanhaesebroeck Ludwig Institute for Cancer Research ; The University of Edinburgh
SKU: 158393
Genetic background: Mice in which exons 21 and 22 from PIK3CB/p110beta are constitutively deleted by crossing to a Cre-deleter strain – backcrossed onto B6 background.
Production details: Mice in which exons 21 and 22 from PIK3CB/p110beta are constitutively deleted by crossing to a Cre-deleter strain – backcrossed onto B6 background.
Additional notes: Homozygous p110bD21-22/D21-22 mice can be obtained. Heterozygous mice show reduced phenotypes of homozygous.
Cat. #: 158393
Research Fields: Cancer
Target: PIK3CB
Model: Knock-Out
Phenotype: Homozygous p110bD21-22/D21-22 mice can be obtained. Heterozygous mice show reduced phenotypes of homozygous.
Shipping conditions: Embryo/Spermatoza- Dry Ice
References:

Kulkarni et al. 2011. Sci Signal. 4(168):ra23. PMID: 21487106.

Guillermet-Guibert et al. 2008. Proc Natl Acad Sci U S A. 105(24):8292-7. PMID: 18544649.

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