| Inventor | Institute |
|---|---|
| Laxmikant Deshpande | Virginia Commonwealth University |
| SKU: | 154268 |
|---|---|
| Product description: | Repeated low-dose organophosphate diisopropyl fluorophosphate (DFP) exposre leads to the development of depression and cognitive impairment in a rat model of Gulf War Illness |
| Production details: | Rats were injected s.c. with 400 Âľg/kg DFP once-daily for 5 days |
| Additional notes: | Male Sprague-Dawley Rats |
| Cat. #: | 154268 |
|---|---|
| Target: | acetylcholinesterase |
| Disease: | Gulf War Illness |
| Zygosity: | unknown |
| Phenotype: | Gulf War Illness |
| References: |
Phillips et al. 2019. Toxicol Sci. 169(2):567-578. PMID: 30859209. Targeting Intracellular Calcium Stores Alleviates Neurological Morbidities in a DFP-Based Rat Model of Gulf War Illness. Phillips et al. 2018. Mil Med. 183(suppl_1):552-555. PMID: 29635560. Chronic Neurological Morbidities and Elevated Hippocampal Calcium Levels in a DFP-Based Rat Model of Gulf War Illness. Phillips et al. 2016. Neurotoxicology. 52:127-33. PMID: 26619911. Repeated low-dose organophosphate DFP exposur… |
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