Gulf War Illness Rat

Contributors

Inventor Institute
Laxmikant Deshpande Virginia Commonwealth University
SKU: 154268
Product description: Repeated low-dose organophosphate diisopropyl fluorophosphate (DFP) exposre leads to the development of depression and cognitive impairment in a rat model of Gulf War Illness
Production details: Rats were injected s.c. with 400 Âľg/kg DFP once-daily for 5 days
Additional notes: Male Sprague-Dawley Rats
Cat. #: 154268
Target: acetylcholinesterase
Disease: Gulf War Illness
Zygosity: unknown
Phenotype: Gulf War Illness
References:

Phillips et al. 2019. Toxicol Sci. 169(2):567-578. PMID: 30859209.

Targeting Intracellular Calcium Stores Alleviates Neurological Morbidities in a DFP-Based Rat Model of Gulf War Illness.

Phillips et al. 2018. Mil Med. 183(suppl_1):552-555. PMID: 29635560.

Chronic Neurological Morbidities and Elevated Hippocampal Calcium Levels in a DFP-Based Rat Model of Gulf War Illness.

Phillips et al. 2016. Neurotoxicology. 52:127-33. PMID: 26619911.

Repeated low-dose organophosphate DFP exposur…

Related Tools for Mouse models

Cat. # Tool Name
151476 Raf-/- KO Mouse Key Info View Tool
151549 Inva3b1 Mouse Key Info View Tool
151556 UNG Mouse Key Info View Tool
151443 GSTP1GSTP2 KO Mouse Key Info View Tool
151477 Raf-1FF/FF knockin mouse Key Info View Tool

Tool enquiry

Please ensure you use your organisation email address rather than personal where possible, as this helps us locate your organisation in our system faster.

Please note we may take up to three days to respond to your enquiry.

CancerTools.org uses the contact information provided to respond to you about our research tools and service. For more information please review our privacy policy.