Home / Tools / Cell lines / Transient receptor potential ankyrin 1 (TRPA1)-GFP HeLa cell line
Transient receptor potential ankyrin 1 (TRPA1)-GFP HeLa cell line
Contributors
Inventor
Institute
Peter Bradding ; Harvinder Virk
University of Leicester
SKU:
158381
Product description:
The transient receptor potential cation channel family member ankyrin 1 (TRPA1) is an ion channel with high Ca2+ permeability that is activated by numerous noxious stimuli and by multiple products of oxidative stress. TRPA1 is a drug target with antagonists in phase I and II clinical trials. It is considered a potential target in multiple pain conditions including neuropathic, inflammatory and migraine pain, in addition to cough sensitivity, airway inflammation and fibrosisThis HeLa cell line is stably transfected with a dual-gene promotor (pCDH-CMV-MCS-EF1-copGFP) to express both GFP and hTRPA1.Forward TRPA1 Xba1 gggtctagaATGAAGCGCAGCCTGAGGAAG Reverse TRPA1 NotI ggggcggccgcttaAGGCTCAAGATGGTGTGTTTTTGCC
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