TOV-3121EP

Cell line derived from solid tumor of patient with Stage 3 IIC fallopian tube-HGSC and had received neo-adjuvant chemotherapy of carboplatin/taxol prior to specimen collection in 2006. Cell line had intermediate sensitivity to carboplatin and did not form SC or IP tumors in NRG mice.

Contributors

Inventor Institute
Anne-Marie Mes-Masson and Diane Provencher Centre Hospitalier de L’université de Montréal
Cat. #: 161902
Cancer types: Ovarian cancer
Research Fields: Cancer
Organism: Human
Tissue: Ovary
Morphology: Formed spheroids with small, compact cores surrounded by loosely aggregated cells with an irregular margin
Growth properties: Mixed
Primary citation: Sauriol, et al. 2020. Cancers(Basel). 8,12(8):2222. PMID: 32784519
Product description: Cell line derived from solid tumor of patient with Stage 3 IIC fallopian tube-HGSC and had received neo-adjuvant chemotherapy of carboplatin/taxol prior to specimen collection in 2006. Cell line had intermediate sensitivity to carboplatin and did not form SC or IP tumors in NRG mice.
CRISPR: No
Production details: Tissue was scraped into 100mm plate with complete OSE medium and maintained for 40 days with weekly culture medium replacement
Disease: Cancer
Format: Frozen
Storage conditions: Liquid Nitrogen
Shipping conditions: Dry Ice
Growth medium: OSE medium, 10% FBS, 0.5ug/ml apmphotericin B and 50ug/ml gentamycin sulfate
Temperature: 37° C
Atmosphere: 7% O2 and 5% CO2
Biosafety level: 1
References:

Meng, et al. 2023. J Anim Sci. 3, 101:skad215. PMID: 37351870

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