Epithelial ovarian cancer cell lines spontaneously derived from solid tumor of patient diagnosed with high-grade serous ovarian cancer
| Inventor | Institute |
|---|---|
| Anne-Marie Mes-Masson and Diane Provencher | Centre Hospitalier de Luniversité de Montréal |
| SKU: | 161778 |
|---|---|
| Product description: | Epithelial ovarian cancer cell lines spontaneously derived from solid tumor of patient diagnosed with high-grade serous ovarian cancer. Sample taken from solid tissue of the ovary, specifically derived from samples of the right ovary |
| Alternate name: | TOV-2929D |
| Gender: | Female |
| CRISPR: | No |
| Production details: | Established using the Scrape method where tumor tissue was scraped into a 100mm plate with complete OSE medium and maintained for 40 days with medium replaced weekly. |
| Additional notes: | Patient 2929 was age 77 at time of diagnosis with prior history of colorectal cancer. Patient was chemonaive at the time of sampling and sampling took place in 2006. |
| Receptors of note: | No |
| Cat. #: | 161778 |
|---|---|
| Cancer types: | Ovarian cancer |
| Research Fields: | Cancer |
| Organism: | Human |
| Tissue: | Derived from solid tumor of patient diagnosed with high-grade serous ovarian cancer at specific time points at diagnosis and relapse |
| Gender: | Female |
| Morphology: | Characteristic flattened cobblestone-like appearance. Formed compact flat discs rather than spherical spheroids. |
| Growth properties: | Adherent |
| Primary citation: | Sauriol A et al. 2020. Cancers. 12(8):2222. PMID: 32784519 |
| Shipping conditions: | Dry Ice |
|---|---|
| Growth medium: | OSE medium contains 10% FBS, 0.5ug/mL amphotericin B and 50 ug/mL gentamicin |
| Temperature: | 37° C |
| Atmosphere: | Low oxygen conditions of 7% O2 and 5% CO2 |
| References: |
Gaia-Oltean et al. 2021. Exp Ther Med. 21(3):243. PMID: 33603851 Canals Hernaez et al. 2020. J Immunother Cancer. 8(2):e001128. PMID: 33243933 Borzdzi?owska et al. 2022. Biomedicines. 11 10(5):1116. PMID: 35625852 Meng et al. 2023. J Anim Sci. 3 101:skad215. PMID: 37351870 Koni et al. 2020. Int J Mol Sci. 18 21(20):7697. PMID: 33080952 |
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