Epithelial ovarian cancer cell line derived from solid tumors of patient who was diagnosted with Stage 3 IIIC ovarian high-grade serous adenocarcinoma had received neo-adjuvant chemotherapy of carboplatin/taxol prior to specimen collection in 2006. Cell line exhibited strong sensitivity to carboplatin. Cell line formed in vivo metastases and ascites when injected IP in mice, but did not form SC tumors. This cell line might be useful for studying disease spread at recurrence.
CRISPR:
No
Production details:
Tissue was scraped into 100mm plate with complete OSE medium and maintained for 40 days with weekly culture medium replacement
Disease:
Cancer
Cat. #:
161901
Cancer types:
Ovarian cancer
Research Fields:
Cancer
Organism:
Human
Tissue:
Ovary
Morphology:
Did not form spheroids
Growth properties:
Mixed
Primary citation:
Sauriol, et al. 2020. Cancers(Basel). 8,12(8):2222. PMID: 32784519
Format:
Frozen
Storage conditions:
Liquid Nitrogen
Shipping conditions:
Dry Ice
Growth medium:
OSE medium, 10% FBS, 0.5ug/ml apmphotericin B and 50ug/ml gentamycin sulfate
Temperature:
37° C
Atmosphere:
7% O2 and 5% CO2
Biosafety level:
1
References:
Guo, et al. 2022. Front Genet. 25, 13:844800. PMID: 35401671
Sauriol, et al. 2020. Cancers(Basel). 8,12(8):2222. PMID: 32784519
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