| Inventor | Institute |
|---|---|
| Anne-Marie Mes-Masson and Diane Provencher | Centre Hospitalier de L’université de Montréal |
| SKU: | 161901 |
|---|---|
| Product description: | Epithelial ovarian cancer cell line derived from solid tumors of patient who was diagnosted with Stage 3 IIIC ovarian high-grade serous adenocarcinoma had received neo-adjuvant chemotherapy of carboplatin/taxol prior to specimen collection in 2006. Cell line exhibited strong sensitivity to carboplatin. Cell line formed in vivo metastases and ascites when injected IP in mice, but did not form SC tumors. This cell line might be useful for studying disease spread at recurrence. |
| CRISPR: | No |
| Production details: | Tissue was scraped into 100mm plate with complete OSE medium and maintained for 40 days with weekly culture medium replacement |
| Disease: | Cancer |
| Cat. #: | 161901 |
|---|---|
| Cancer types: | Ovarian cancer |
| Research Fields: | Cancer |
| Organism: | Human |
| Tissue: | Ovary |
| Morphology: | Did not form spheroids |
| Growth properties: | Mixed |
| Primary citation: | Sauriol, et al. 2020. Cancers(Basel). 8,12(8):2222. PMID: 32784519 |
| Format: | Frozen |
|---|---|
| Storage conditions: | Liquid Nitrogen |
| Shipping conditions: | Dry Ice |
| Growth medium: | OSE medium, 10% FBS, 0.5ug/ml apmphotericin B and 50ug/ml gentamycin sulfate |
| Temperature: | 37° C |
| Atmosphere: | 7% O2 and 5% CO2 |
| Biosafety level: | 1 |
| References: |
Guo, et al. 2022. Front Genet. 25, 13:844800. PMID: 35401671 Sauriol, et al. 2020. Cancers(Basel). 8,12(8):2222. PMID: 32784519 |
|---|
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