T47D-STn Cell Line

The tumour cell line, T47D-STn, was created as a breast cancer model which expresses the Sialyl-Tn, STn, antigen.

Contributors

Inventor Institute
Joy Burchell ; Joyce Taylor-Papadimitriou King's College London
SKU: 153170
Product description: The parental T47D cell line was established from the pleural effusion of a ductal carcinoma of the breast. The tumour cell line, T47D-STn, was created as a breast cancer model…
Gender: Male
CRISPR: Yes
Conditional: No
Parental cell line: T47D
Disease: Cancer
Cat. #: 153170
Provenance and Ownership: The T47D-STn Cell Line is owned by Cancer Research UK. CancerTools supplies the T47D-STn Cell Line under licence from Cancer Research UK and is the authorised source for its distribution. Sourcing T47D-STn Cell Line directly from the IP owner ensures authenticity, provenance and compliance with all applicable licensing and research use requirements.
Tool sub type: Continuous
Unit size: 1×10^6 cells / vial
Cancer types: Breast cancer
Research Fields: Cancer; Drug development
Organism: Human
Tissue: Breast
Gender: Male
Format: Frozen
Storage conditions: Liquid Nitrogen
Shipping conditions: Dry ice
Growth medium: DMEM 10% FCS, 500 ?g/ml G418, 300 ?g/ml hygromycin
Mycoplasma free: Yes
Biosafety level: 1
References:

Sewell et al. 2006. J Biol Chem. 281(6):3586-94. PMID: 16319059.

The ST6GalNAc-I sialyltransferase localizes throughout the Golgi and is responsible for the synthesis of the tumor-associated sialyl-Tn O-glycan in human breast cancer.

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