| Inventor | Institute |
|---|---|
| Lloyd J. Old, Germain Trempe | Memorial Sloan-Kettering Cancer Center (MSK) |
| SKU: | 161915 |
|---|---|
| Product description: | SK-MEL-2 is one of a series of melanoma cell lines established from patient-derived tumour samples. This cell line expresses wildtype B-Raf and mutant N-Ras (Q61R). |
| Gender: | Male |
| Model description: | Tumourigenic in nude mice; forms malignant melanoma |
| Products or characteristics of interest: | Karyotype: (P6) hypodiploid to hypertetraploid with abnormalities including dicentrics, secondary constrictions and large telocentric marker. Note: Cytogenetic information is based on initial seed stock at ATCC. Cytogenetic instability has been reported in the literature for some cell lines. Isoenzymes: AK-1, 1; ES-D, 1; G6PD, B; GLO-I, 2; PGM1, 1; PGM3, 1 |
| Cat. #: | 161915 |
|---|---|
| Cancer types: | Skin cancer |
| Organism: | Human |
| Tissue: | Skin |
| Gender: | Male |
| Model: | Tumourigenic |
| Morphology: | Polygonal |
| Growth properties: | Adherent |
| Primary citation: | Fogh et al. 1977. Journal of the National Cancer Institute. 59: 221-226. PMID: 327080 |
| Storage conditions: | Vapor phase of liquid nitrogen |
|---|---|
| Shipping conditions: | Dry Ice |
| Growth medium: | EMEM supplemented with FBS to a final concentration of 10% |
| Temperature: | 37° C |
| Atmosphere: | 5% CO2 in air |
| Storage medium: | Complete growth medium supplemented with 5% (v/v) DMSO |
| Biosafety level: | 1 |
| References: |
Xing et al. 2012. Oncogene. 31(4):446-457. PMID: 21725359 |
|---|
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