OV-2085 cell line

Epthelial ovarian cancer cell line derived from high grade serous carcinoma ascite

Contributors

Inventor Institute
Anne-Marie Mes-Masson and Diane Provencher Centre Hospitalier de L’université de Montréal
SKU: 161772
Product description: Epthelial ovarian cancer cell line derived from high grade serous carcinoma ascites. Cell line produces tumors in mice upon SC injection
Alternate name: OV-2085
Gender: Female
CRISPR: No
Production details: Patient ascites were centrifuged and seeded in 100mm plate with OSE medium and maintained for 40 days with weekly media replacement.
Additional notes: Patient 2085 had family history of breast cancer, no BRCA mutation, and was age 63 at age of diagnosis. Patient received carboplatin and Paclitaxel prior to sampling. Sampling took place in 2004
Cellosaurus ID: CVCL_A1SI
Receptors of note: No
Cat. #: 161772
Cancer types: Ovarian cancer
Research Fields: Cancer
Organism: Human
Tissue: Derived from ascites of patient with high grade serous carcinoma
Gender: Female
Morphology: Homogenous morphology after 60 passages – small clusters of loosely attached round cells growing perpendicularly to culture plate
Growth properties: Adherent
Primary citation: Sauriol A et al. 2020. Cancers. 12(8):2222. PMID: 32784519
Shipping conditions: Dry Ice
Growth medium: OSE medium contains 10% FBS, 0.5ug/mL amphotericin B and 50 ug/mL gentamicin
Temperature: 37° C
Atmosphere: Low oxygen conditions of 7% O2 and 5% CO2
References:

Gaia-Oltean et al. 2021. Exp Ther Med. 21(3):243. PMID: 33603851 Canals Hernaez et al. 2020. J Immunother Cancer. 8(2):e001128. PMID: 33243933 Borzdzi?owska et al. 2022. Biomedicines. 11

10(5):1116. PMID: 35625852 Meng et al. 2023. J Anim Sci. 3

101:skad215. PMID: 37351870 Koni et al. 2020. Int J Mol Sci. 18

21(20):7697. PMID: 33080952

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