Fourth generation cell line derived from an ipsilateral brachial lymph node metastasis of a third-generation line
Gender:
Female
CRISPR:
No
Production details:
Line was isolated from a brachial lymph node metastasis after roughly one month of growth of a LN3 tumor
Parental cell line:
B16-F0
Model description:
A luciferase transgene was integrated into the B16-F0 parental line, but is no longer expressed in LN metastatic progeny. WES suggests the presence of Braf and Pten mutations.
Disease:
Melanoma
Cat. #:
162229
Cancer types:
Skin cancer
Organism:
Mouse
Tissue:
Skin (lymph node metastasis)
Gender:
Female
Model:
Tumorigenic cell line; syngeneic
Morphology:
Mixed morphology that is predominantly spindle-shaped
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