MEF OGG1 KO Cell Line

Exclusive Tool

The MEF OGG1 KO cell line can be used to assess the role of the mammalian enzyme OGG1 in repair of DNA damage and prevention of carcinogenesis

Contributors

Inventor Institute
Tomas Lindahl Cancer Research UK, London Research Institute: Clare Hall Laboratories
SKU: 151846
Product description: The MEF OGG1 KO cell line can be used to assess the role of the mammalian enzyme OGG1 in repair of DNA damage and prevention of carcinogenesis. the cell line can be used to assess the incidence and consequences of 8-oxoG formation in the mammalian genome.
Cellosaurus ID: CVCL_6E74
Cat. #: 151846
Provenance and Ownership: The MEF OGG1 KO Cell Line is owned by Cancer Research UK. CancerTools supplies the MEF OGG1 KO Cell Line under licence from Cancer Research UK and is the authorised source for its distribution. Sourcing MEF OGG1 KO Cell Line directly from the IP owner ensures authenticity, provenance and compliance with all applicable licensing and research use requirements.
Unit size: 1×10^6 cells / vial
Organism: Mouse
Tissue: Embryo
Model: Knock-Out
Format: Frozen
Shipping conditions: Dry ice
Growth medium: DMEM/Ham’s F-12 (3:1) with 10% FBS
References:

Klungland et al. 1999. Proc Natl Acad Sci U S A. 96(23):13300-5. PMID: 10557315.

Accumulation of premutagenic DNA lesions in mice defective in removal of oxidative base damage.

Images

View Gallery
MEF OGG1 KO Cell Line. Early log phase. Image courtesy of the European Collection of Authenticated Cell Cultures (ECACC)

Related Tools for Cell lines

Cat. # Tool Name
151577 OGG1 KO Mouse Key Info View Tool

Tool enquiry

Please ensure you use your organisation email address rather than personal where possible, as this helps us locate your organisation in our system faster.

Please note we may take up to three days to respond to your enquiry.

CancerTools.org uses the contact information provided to respond to you about our research tools and service. For more information please review our privacy policy.