MC38-L colorectal mouse tumour cell line

MC38-L is the Leiden subclone of the well-established murine colon adenocarcinoma cell line MC38.

Contributors

Inventor Institute
Ferry Ossendorp Leiden University Medical Center
Cat. #: 162493
Tool sub type: Primary
Cancer types: Colorectal cancer
Research Fields: Cancer
Organism: Mouse
Gender: Female
Primary citation: Falk et al. 1991. Nature. 351:290-296. PMID: 1709722.
Alternate name: MC38-L cell line; MC-38-L cell line; Mouse Colon 38 L cell line
Product description: Colorectal cell line used as a model for optimising and development of new immunotherapeutic strategies as it is sensitive for most immune checkpoint therapies.
Gender: Female
CRISPR: Yes
Conditional: No
Format: Frozen
Growth medium: IMDM medium supplemented with 8% foetal calf serum, 100 IU/mL penicillin/streptomycin , 2 mM L-glutamine and 25 µM 2-mercaptoethanol.
Mycoplasma free: Yes
References:

Schrörs et al. 2023. Front Immunol. 8:14:1102282. PMID: 36969213.

Yadav et al. 2014. Nature. 27

515(7528):572-576. PMID: 25428506.

Hos et al. 2019. Oncoimmunology. 13

9(1):1673125. PMID: 32923109.

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