LF2 Cell Line

LF2 Cell Line: a germ-line competent embryonic stem cell line that inactivates one of its X chromosomes upon retinoic acid treatment.

Contributors

Inventor Institute
Jennifer Nichols University of Oxford
SKU: 152568
Product description: The LF2 mouse embryonic stem cell line is a germ-line competent embryonic stem cell line that inactivates one of its X chromosomes upon retinoic acid treatment. Embryonic stem cells provide a powerful system for the experimental analysis of mammalian development. Their genetic manipulation allows the introduction of defined modifications into the mouse germ-line, whilst in culture they constitute both an assay system for, and a potential source of, embryonic regulatory factors.
Conditional: No
Cellosaurus ID: CVCL_AS05
Cat. #: 152568
Provenance and Ownership: The LF2 Cell Line is owned by Cancer Research UK. CancerTools supplies the LF2 Cell Line under licence from Cancer Research UK and is the authorised source for its distribution. Sourcing LF2 Cell Line directly from the IP owner ensures authenticity, provenance and compliance with all applicable licensing and research use requirements.
Unit size: 1×10^6 cells / vial
Research Fields: Genetics; Stem cell biology
Organism: Mouse
Tissue: Embryo
Format: Frozen
Shipping conditions: Dry ice
Growth medium: Embryonic bodies were formed by growing cells in low adherence dishes in DMEM+FBS for 10 days.
References:

Evans et al. Development 110, 1341-1348 (1990).

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