CEACAM-6 is expressed by granulocytes and their precursors. Activation enhances surface expression by mobilizing CEACAM-6 from storage in azurophilic granules.
| Institute |
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| LeukoCom |
| SKU: | 160695 |
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| Product description: | CEACAM-6 is expressed by granulocytes and their precursors. Activation enhances surface expression by mobilizing CEACAM-6 from storage in azurophilic granules. It often shows aberrant expression in acute lymphocytic leukaemia’s. CEACAM-6 is also expressed in epithelia of various organs and is upregulated in pancreatic and colon adenocarcinomas and hyperplastic polyps. Over-expression confers resistance to adhesion-related apoptosis (anoikis) in tumour cells |
| Alternate name: | Carcinoembryonic antigen-related cell adhesion molecule 6, CD66c, Cluster of Differentiation 66c |
| Conditional: | No |
| Production details: | Overexpression of human CEACAM6-Fc Chimera Protein |
| Cellosaurus ID: | CVCL_C0EK |
| Parental cell line: | HEK293 |
| Cat. #: | 160695 |
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| Tool sub type: | Continuous |
| Unit size: | 1×10^6 cells / vial |
| Research Fields: | Cancer;Cell biology |
| Organism: | Human |
| Tissue: | Kidney |
| Model: | Transgenic |
| Growth properties: | Adherent |
| Format: | Frozen |
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| Storage conditions: | Liquid Nitrogen |
| Shipping conditions: | Dry ice |
| Growth medium: | DMEM + 10% FBS |
| Recommended controls: | HEK293 parental line |
| Mycoplasma free: | Yes |
| Biosafety level: | 1 |
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