Home / Tools / Cell lines / HEK293-CEACAM1-dN-Fc (without N domain) cell line
HEK293-CEACAM1-dN-Fc (without N domain) cell line
Contributors
Inventor
Institute
Bernhard Singer
LeukoCom
SKU:
160686
Product description:
CEACAM-1, also known as CD66a, is an immunoglobulin superfamily protein that is expressed on neutrophils, activated NK cells, bile duct and colonic epithelial cells, and endothelial cells. CEACAM-1 is heavily glycosylated and carries high mannose residues and (sialyl) Lewis-x. It is expressed as at least three soluble and seven transmembrane isoforms, with variations occurring in both the ECD and cytoplasmic region. It engages in homotypic adhesion and heterotypic adhesion with CEACAM-3/CD66d…
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