Family 1 mother – LAD-III Lymphoblastoid Cell Line

Exclusive Tool

An EBV-transformed B lymphoblastoid cell line (LCL) derived from the mother of a Maltese subject that has Leukocyte Adhesion Deficiency-III (LAD-III) with a mutation in the kindlin-3 gene.

Contributors

Inventor Institute
Nancy Hogg Cancer Research UK, London Research Institute: Lincoln's Inn Fields
SKU: 153764
Product description: An EBV-transformed B lymphoblastoid cell line (LCL) derived from the mother of a Maltese subject that has Leukocyte Adhesion Deficiency-III (LAD-III) with a mutation in the kindlin-3 gene. LCLs are also available from the subject, father and subject’s sister. This cell line was derived from ‘Family 1 mother’ as described in Svensson et al. 2009. N.Nat Med. 2009 Mar;15(3):306-12. PMID: 1923446
Alternate name: Fermitin family homolog 3, MIG2-like protein, Unc-112-related protein 2
Cellosaurus ID: CVCL_VP09
Disease: Cancer
Cat. #: 153764
Provenance and Ownership: The Family 1 mother – LAD-III Lymphoblastoid Cell Line is owned by Cancer Research UK. CancerTools supplies the Family 1 mother – LAD-III Lymphoblastoid Cell Line under licence from Cancer Research UK and is the authorised source for its distribution. Sourcing Family 1 mother – LAD-III Lymphoblastoid Cell Line directly from the IP owner ensures authenticity, provenance and compliance with all applicable licensing and research use requirements.
Unit size: 1×10^6 cells / vial
Research Fields: Cell biology;Immunology
Organism: Human
Tissue: Blood
Growth properties: Suspension, lymphoblastoid cell line
Cancer Types In Detail: Leukocyte Adhesion Deficiency-III (LAD-III)
Format: Frozen
Storage conditions: Liquid Nitrogen
Shipping conditions: Dry ice
Growth medium: RPMI-1640 + 10% FCS
Mycoplasma free: Yes
Biosafety level: 1
References:

Svensson et al. 2009. Nat Med. 15(3):306-12. PMID: 19234463.

Leukocyte adhesion deficiency-III is caused by mutations in KINDLIN3 affecting integrin activation.

Related Tools for Cell lines

Cat. # Tool Name
153765 Family 1 father – LAD-III Lymphoblastoid Cell Line Key Info View Tool
153766 Family 1 subject – LAD-III Lymphoblastoid Cell Line Key Info View Tool
153763 Family 1 sibling – LAD-III Lymphoblastoid Cell Line Key Info View Tool

Related News

UM-UC-10 Cell Line. Image courtesy of the European Collection of Authenticated Cell Cultures (ECACC), UK.
Cell Lines

Popular cell lines now available only from CancerTools.org

Read More
Cell Lines

New cell lines: murine melanocyte and melanoblast cell lines from Dr. Elena Sviderskaya

Read More
Image Reference: 2x PTEN -/- mouse prostate cancer cell lines (MuCap system). Histology staining of syngraft tumours (Van Duijn et al., 2018).
Cell Lines

38 new prostate cancer cell lines

Read More

Tool enquiry

Please ensure you use your organisation email address rather than personal where possible, as this helps us locate your organisation in our system faster.

Please note we may take up to three days to respond to your enquiry.

CancerTools.org uses the contact information provided to respond to you about our research tools and service. For more information please review our privacy policy.