| Inventor | Institute |
|---|---|
| Martin Clynes | Dublin City University |
| SKU: | 157660 |
|---|---|
| Product description: | Mesenchymal-like sub-population cloned at NCTCC from DLKP P5, about 5% of DLKP cells show DLKP-M morphology, interconversion with -I, closest to normal chromosome number, fold resistance comp. to DLKP: 0.8 Adr; 0.95 Vcr; 0.7 VP-16. Immunocytochemistry: cytokeratin (all)-; GFAP-vimentin+; neurofilament+; P-gp-; a2- integrin++; 703D4+; 704A1 +; desmin-. More invasive in vitro than DLKP-SQ. |
| Production details: | Single cell cloning from DLKP parental population |
| Cellosaurus ID: | CVCL_H739 |
| Parental cell line: | DLKP |
| Disease: | Cancer |
| Cat. #: | 157660 |
|---|---|
| Tool sub type: | Continuous |
| Unit size: | 1×10^6 cells / vial |
| Cancer types: | Lung cancer |
| Research Fields: | Cancer |
| Organism: | Human |
| Tissue: | Lung |
| Growth properties: | Monolayer |
| Cancer Types In Detail: | Lung carcinoma |
| Format: | Frozen |
|---|---|
| Storage conditions: | Liquid Nitrogen |
| Shipping conditions: | Dry ice |
| Growth medium: | DMEM/Ham’s F12, 5% FCS. Split 1:5, medium change 2-3 times weekly. Freezing method: 10% DMSO in FBS |
| Recommended controls: | DLKP parental line |
| Mycoplasma free: | Yes |
| Biosafety level: | 1 |
| References: |
O'Sullivan et al. 2014. Tumour Biol. 35(7):6983-97. PMID: 24744142. Keenan et al. 2012. Exp Cell Res. 318(5):593-602. PMID: 22281030. McBride et al. 1998. Tumour Biol. 19(2):88-103. PMID: 9486560. |
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