CMT 64/61 Cell Line

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The tumourigenic and metastatic CMT 64/61 murine cell line is derived from an alveologenic lung carcinoma of a C57BL/1CRF mouse.

Contributors

Inventor Institute
Peter Riddle Cancer Research UK, London Research Institute: Lincoln's Inn Fields
SKU: 152751
Product description: The tumourigenic and metastatic CMT 64/61 murine cell line is derived from an alveologenic lung carcinoma of a C57BL/1CRF mouse, and demonstrates.a stable morphology and growth rate comparable to that observed in the original tumour tissue in vitro. The cell line retains similar characteristics both in culture and in lung metastases following subcutaneous inoculation in mice. This demonstrates its consistency and reliability as a model for studying lung carcinoma progression and metastasis.
Gender: Female
Conditional: Yes
Production details: Isolated from a primary alveogenic lung carcinoma tumour in a C57BL/1CRF mouse. The cell line maintained a stable morphology and growth rate comparable to that observed in the original tumour tissue in vitro. The cell line retained similar characteristics both in culture and in lung metastases following subcutaneous inoculation in mice.
Cellosaurus ID: CVCL_4146
Disease: Cancer
Cat. #: 152751
Provenance and Ownership: The CMT 64/61 Cell Line is owned by Cancer Research UK. CancerTools supplies the CMT 64/61 Cell Line under licence from Cancer Research UK and is the authorised source for its distribution. Sourcing CMT 64/61 Cell Line directly from the IP owner ensures authenticity, provenance and compliance with all applicable licensing and research use requirements.
Unit size: 1×10^6 cells / vial
Cancer types: Lung cancer
Organism: Mouse
Tissue: Lung
Gender: Female
Model: Cancer cell line
Growth properties: Adherent
Primary citation: Franks et al. 1976. Cancer Res. 36(3):1049-1055. PMID: 1253168.
Format: Frozen
Shipping conditions: Dry ice
Growth medium: DMEM with 2mM Glutamine and 10% FCS.
Subculture routine: Split sub-confluent cultures (70-80%) 1:3 to 1:6 i.e. seeding at 2-4×10,000 cells/cm2, using 0.25% trypsin or trypsin/EDTA; 5% CO2; 37°C. Please also see detailed protocol within the Product Datasheet in the Documentation section below.
References:

Franks et al. 1976. Cancer Res. 36(3):1049-55. PMID: 1253168

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