BR58 cell line

This is an ovary cancer patient’s derived cell line. Histology of serous papillary carcinoma. The line is derived from breast metastasis and it is positive for the BRCA1 c.68_69delAG, p.Glu23Valfs*17 (185delAG) mutation. When implanted to NSG mice it forms tumors. This line can serve as a platform for drug screening for cancer cells in vitro and in vivo.

Contributors

Inventor Institute
Tamar Peretz Hadassah Medical Center; Hadasit Medical Research Services and Development Ltd.
Cat. #: 157975
Tool sub type: 10XUAS IVS p10
Unit size: 1×10^6 cells / vial
Cancer types: Ovarian cancer
Organism: Human
Tissue: Breast
Gender: Male
Model: Tumour line
Product description: This is an ovary cancer patient's derived cell line. Histology of serous papillary carcinoma. The line is derived from breast metastasis and it is positive for the BRCA1 c.68_69delAG, p.Glu23Valfs*17 (185delAG) mutation. When implanted to NSG mice it forms tumors. This line can serve as a platform for drug screening for cancer cells in vitro and in vivo.
Gender: Male
CRISPR: Yes
Conditional: Yes
Production details: The cells were derived from metastasis (pleural effusion) in a patient with serous papillary carcinoma.
Format: Frozen
Shipping conditions: Dry ice
Growth medium: The base medium for this cell line is DMEM with 10% bovine serum.
Mycoplasma free: Yes

Images

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BR58 Cell Line - image captured with a x10 objective lens.

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