A549p0#1a Cell Line

Derived from A549 human lung adenocarcinoma cell line, the A549p0#1a Cell Line lacks both mitochondrial DNA (mtDNA) and a functional mitochondrial electron transport chain and is auxotrophic for uridine and pyruvate. These cells can be repopulated with exogenous mtDNA (e.g., mtDNA from patients with mitochondrial disease) allowing for mitochondrial mutational analysis._x000D_ _x000D_ The original parental […]

Contributors

Inventor Institute
Mikhail Alexeyev University of South Alabama
Cat. #: 160508
Unit size: 1×10^6 cells / vial
Cancer types: Lung cancer
Research Fields: Drug development;Genetics;Metabolism
Organism: Human
Tissue: Lung
Product description: Derived from A549 human lung adenocarcinoma cell line, these cells lack both mitochondrial DNA (mtDNA) and a functional mitochondrial electron transport chain and are auxotrophic for uridine and pyruvate. These cells can be repopulated with exogenous mtDNA (e.g., mtDNA from patients with mitochondrial disease) allowing for mitochondrial mutational analysis. The original parental lines are available upon request.
Conditional: No
Parental cell line: A549
Disease: Mitochondrial Disease
Format: Frozen
Shipping conditions: Dry ice

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