2C4 cell line

The 2C4 cell line is a clonal derivative of the human fibrosarcoma cell line HT 1080. The 2C4 cell line clone expresses the simple cell-surface marker CD2 (normally expressed only on T cells) under the control of the 9-27 gene promoter. The 9-27 gene promoter is inducible by interferon gamma.

Contributors

Inventor Institute
George Stark ; Ian Kerr Cancer Research UK, London Research Institute: Lincoln's Inn Fields
Cat. #: 154235
Tool sub type: Continuous
Unit size: 1×10^6 cells / vial
Research Fields: Cancer;Cell signaling and signal transduction;Immunology
Organism: Human
Cancer Types In Detail: Fibrosarcoma
Product description: The 2C4 cell line is a clonal derivative of the human fibrosarcoma cell line HT 1080. The 2C4 cell line clone expresses the simple cell-surface marker CD2 (normally expressed only on T cells) under the control of the 9-27 gene promoter. The 9-27 gene promoter is inducible by interferon gamma.
Cellosaurus ID: CVCL_1D50
Parental cell line: HT 1080
Disease: Cancer
Format: Frozen
Storage conditions: Liquid Nitrogen
Shipping conditions: Dry ice
Growth medium: DMEM + 10% heat-inactivated FBS + 400ug G418 per ml (As described by Kohlhuber et al., 1997)
Mycoplasma free: Yes
Biosafety level: 1
References:

Kohlhuber et al. 1997. Mol Cell Biol. 17(2):695-706. PMID: 9001223.

Watling et al. 1993. Nature. 366(6451):166-70. PMID: 7901766.

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