Anti-Tumor Necrosis Factor (TNF-a) [12F6]

Tumor necrosis factor is a cell signaling protein or cytokine that is involved in inflammation, and specifically one of the proteins in the acute phase reaction.

Contributors

Inventor Institute
Royal McGraw University of Georgia
SKU: 153869
Product description: Tumor necrosis factor is a cell signaling protein or cytokine that is involved in inflammation, and specifically one of the proteins in the acute phase reaction. TNF is produced mainly by macrophages but other white cells too. Some of its roles are to induce fever, apoptotic cell death, inhibit tumorigenesis and inflammation. Diseases associated with dysregulation of TNF production include inflammatory bowel disease (IBD), Psoriasis, Alzheimer’s and cancer.
Alternate name: TNF-?
Conjugation: Unconjugated
Isotype: IgG2b
Immunogen: Protein
Cat. #: 153869
Tool sub type: Primary antibody
Unit size: 100 ug
Research Fields: Apoptosis and autophagy; Cell signaling and signal transduction
Application: ELISA ; IP ; WB
Target: Tumor Necrosis Factor- alpha
Reactivity: Horse
Host: Mouse
Class: Monoclonal
Target background: Tumor necrosis factor is a cell signaling protein or cytokine that is involved in inflammation, and specifically one of the proteins in the acute phase reaction. TNF is produced mainly by macrophages but other white cells too. Some of its roles are to induce fever, apoptotic cell death, inhibit tumorigenesis and inflammation. Diseases associated with dysregulation of TNF production include inflammatory bowel disease (IBD), Psoriasis, Alzheimer’s and cancer.
Format: Liquid
Shipping conditions: Dry ice
References:

Su et al. 1992. Hybridoma. 11(6):715-27. PMID: 1284121.

Equine tumor necrosis factor alpha: cloning and expression in Escherichia coli, generation of monoclonal antibodies, and development of a sensitive enzyme-linked immunosorbent assay.

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