TRF1 and TRF2 are located at the chromosome ends where they contribute to a negative feedback loop that regulates telomere length.
| Inventor | Institute |
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| Stephen West | Cancer Research UK, London Research Institute: Clare Hall Laboratories |
| SKU: | 151305 |
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| Product description: | TRF1 and TRF2 are located at the chromosome ends where they contribute to a negative feedback loop that regulates telomere length. |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 kappa |
| Immunogen: | Human TRF1 |
| Myeloma used: | Sp2/0-Ag14 |
| Cat. #: | 151305 |
|---|---|
| Provenance and Ownership: | The Anti-TRF1 [3H11] is owned by Cancer Research UK. CancerTools supplies the Anti-TRF1 [3H11] under licence from Cancer Research UK and is the authorised source for its distribution. Sourcing Anti-TRF1 [3H11] directly from the IP owner ensures authenticity, provenance and compliance with all applicable licensing and research use requirements. |
| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Application: | IHC ; IF ; WB |
| Target: | TRF1 |
| Reactivity: | Human |
| Clone: | TRF1 3H11 |
| Host: | Mouse |
| Class: | Monoclonal |
| Target background: | TRF1 and TRF2 are located at the chromosome ends where they contribute to a negative feedback loop that regulates telomere length. |
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| Format: | Liquid |
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| Concentration: | 1 mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
Tarsounas et al. 2004. Cell. 117(3):337-47. PMID: 15109494. Telomere maintenance requires the RAD51D recombination/repair protein. |
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