Antibody for TRAF1, also known as Tumor Necrosis Factor Receptor-Associated Factor 1 or TNF receptor (TNFR) associated factor 1. The protein complex formed by this protein and TRAF2 also interacts with inhibitor-of-apoptosis proteins (IAPs), and mediates the anti-apoptotic signals from TNF receptors. TRAF1 has been linked to various cancer types including blood cancer.
| Institute |
|---|
| Helmholtz Munich Core Facility Monoclonal Antibodies |
| SKU: | 162382 |
|---|---|
| Product description: | Antibody for TRAF1, also known as Tumor Necrosis Factor Receptor-Associated Factor 1 or TNF receptor (TNFR) associated factor 1. The protein complex formed by this protein and TRAF2 also interacts with inhibitor-of-apoptosis proteins (IAPs), and mediates the anti-apoptotic signals from TNF receptors. TRAF1 has been linked to various cancer types including blood cancer. |
| Alternate name: | Anti TRAF1 monoclonal antibody (clone TRAF1-1F3) |
| Conjugation: | Unconjugated |
| Isotype: | IgG2a |
| Immunogen: | TRAF1-GST fusion protein |
| Cat. #: | 162382 |
|---|---|
| Tool sub type: | Primary antibody |
| Cancer types: | Blood cancer |
| Research Fields: | Cancer;Cell biology;Cell signaling and signal transduction |
| Application: | WB |
| Target: | TRAF1 |
| Reactivity: | Human |
| Clone: | TRAF1-1F3 |
| Host: | Rat |
| Class: | Monoclonal |
| Primary citation: | Siegler et al. 2003. Mol. Pathol. 56: 156-161. PMID: 12782762 |
| Target background: | TRAF1, also known as Tumor Necrosis Factor Receptor-Associated Factor 1 or TNF receptor (TNFR) associated factor 1. The protein complex formed by this protein and TRAF2 also interacts with inhibitor-of-apoptosis proteins (IAPs), and mediates the anti-apoptotic signals from TNF receptors. TRAF1 has been linked to various cancer types including blood cancer. |
|---|
| References: |
Siegler et al. 2003. Mol. Pathol. 56: 156-161. PMID: 12782762 |
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