SHIP-1 p145 (SH2-containing-inositol phosphatase), associates with activated Fms.
| Inventor | Institute |
|---|---|
| Larry Rohrschneider | Fred Hutchinson Cancer Center |
| Cat. #: | 161664 |
|---|---|
| Tool sub type: | Primary antibody |
| Research Fields: | Cell biology |
| Application: | WB, IP, IF, IHC(P), |
| Target: | SHIP-1 |
| Reactivity: | Mouse,rat,human |
| Clone: | P1C1 |
| Host: | Mouse |
| Class: | Monoclonal |
| Primary citation: | Lucas et al.1999. Blood. 93(6):1922-33. PMID: 10068665 |
| Product description: | Antibody P1C1 is recommended for detection of SHIP-1 protein of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA. SHIP-1 Antibody (P1C1) is an IgG1 ? mouse monoclonal SHIP-1 antibody (also designated INPP5D antibody, or SHIP1 antibody). SHIP-1 contains two phosphotyrosine-binding domains (PTB), a unique amino terminal SH2 domain, a proline-rich region, and two highly conserved motifs found among inositol phosphate 5-phosphatases. SHIP-1 displays both phosphatidylinositol 3,4,5-triphosphate and inositol 1,3,4,5-tetrakisphosphate polyphosphate 5-phosphatase activity. |
|---|---|
| Isotype: | IgG1,? |
| Molecular weight: | 135-145 kDa |
| Target background: | SHIP-1 p145 /SHIP-1 p145 (SH2-containing-inositol phosphatase), associates with activated Fms. SHIP-1 contains two phosphotyrosine-binding domains (PTB), a unique amino terminal SH2 domain, a proline-rich region, and two highly conserved motifs found among inositol phosphate 5-phosphatases. SHIP-1 displays both phosphatidylinositol 3, 4, 5- triphosphate and inositol 1, 3, 4, 5-tetrakisphosphate polyphosphate 5-phosphatase activity. |
|---|
| Storage conditions: | Store at 4° C, **DO NOT FREEZE**. Stable for one year from the date of shipment. Non-hazardous. No MSDS required |
|---|---|
| Shipping conditions: | Dry ice |
| References: |
Lucas et al.1999.Blood.93(6):1922-33.PMID: 10068665 |
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