Serum amyloid A (SAA) proteins are a family of apolipoproteins associated with high-density lipoprotein (HDL) in plasma. SAA is a highly conserved, acute-phase protein (APP) synthesized predominantly by the liver. Different isoforms of SAA are expressed constitutively (constitutive SAAs, SAA4, 5) at different levels or in response to inflammatory stimuli (acute phase SAAs, SAA1-3). SAA proteins also exhibit significant immunological activity by, for example, inducing the synthesis of several cytokines and by being chemotactic for neutrophils and mast cells. SAAs are reported as a potential target in the treatment of diseases associated with inflammation. In salmon, SAA-5 has been indicated…
| Inventor | Institute |
|---|---|
| Abdo Alnabulsi | Vertebrate Antibodies Limited |
| SKU: | 158036 |
|---|---|
| Product description: | Serum amyloid A (SAA) proteins are a family of apolipoproteins associated with high-density lipoprotein (HDL) in plasma. SAA is a highly conserved, acute-phase protein (APP) synthesized predominantly by the liver. Different isoforms of SAA are expressed constitutively (constitutive SAAs, SAA4, 5) at different levels or in response to inflammatory stimuli (acute phase SAAs, SAA1-3). SAA proteins also exhibit significant immunological activity by, for example, inducing the synthesis of several cytokines and by being chemotactic for neutrophils and mast cells. SAAs are reported as a potential target in the treatment of diseases associated with inflammation. In salmon, SAA-5 has been indicated as a main acute phase response (APR) protein post 24 h in which SAA-5 is significantly induced in liver. This is a significant health marker. |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 kappa |
| Molecular weight: | 13 |
| Immunogen: | Ovalbumin-conjugated synthetic peptide. Peptide immunogen is conserved in salmonids fish species. |
| Cat. #: | 158036 |
|---|---|
| Unit size: | 100 ug |
| Research Fields: | Cell biology;Immunology |
| Application: | ELISA ; IHC ; WB |
| Target: | Serum amyloid A-5 (SAA5) |
| Reactivity: | Salmonids |
| Host: | Mouse |
| Class: | Monoclonal |
| Target background: | Serum amyloid A (SAA) proteins are a family of apolipoproteins associated with high-density lipoprotein (HDL) in plasma. SAA is a highly conserved, acute-phase protein (APP) synthesized predominantly by the liver. Different isoforms of SAA are expressed constitutively (constitutive SAAs, SAA4, 5) at different levels or in response to inflammatory stimuli (acute phase SAAs, SAA1-3). SAA proteins also exhibit significant immunological activity by, for example, inducing the synthesis of several cytokines and by being chemotactic for neutrophils and mast cells. SAAs are reported as a potential target in the treatment of diseases associated with inflammation. In salmon, SAA-5 has been indicated as a main acute phase response (APR) protein post 24 h in which SAA-5 is significantly induced in liver. This is a significant health marker. |
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| Format: | Liquid |
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| Shipping conditions: | Dry ice |
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