| Inventor | Institute |
|---|---|
| Nancy Hogg | Cancer Research UK, London Research Institute: Lincoln's Inn Fields |
| SKU: | 153162 |
|---|---|
| Product description: | S100A9, together with heterodimeric partner S100A8, is a major biomarker of inflammation both in released form in serum and through increased expression in epithelial tissue and in many tumours. |
| Alternate name: | MRP-14, calgranulin B |
| Conjugation: | Unconjugated |
| Molecular weight: | 14 kDa |
| Immunogen: | Recombinant human S100-A9 (MRP-14) |
| Cat. #: | 153162 |
|---|---|
| Provenance and Ownership: | The Anti-S100A9 [NH3] is owned by Cancer Research UK. CancerTools supplies the Anti-S100A9 [NH3] under licence from Cancer Research UK and is the authorised source for its distribution. Sourcing Anti-S100A9 [NH3] directly from the IP owner ensures authenticity, provenance and compliance with all applicable licensing and research use requirements. |
| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Cancer; Cell signaling and signal transduction; Immunology |
| Application: | IHC ; WB |
| Target: | S100A9 |
| Reactivity: | Human |
| Clone: | NH3 |
| Host: | Rabbit |
| Class: | Polyclonal |
| Target background: | S100A9, together with heterodimeric partner S100A8, is a major biomarker of inflammation both in released form in serum and through increased expression in epithelial tissue and in many tumours. |
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| Format: | Liquid |
|---|---|
| Concentration: | 0.9-1.1 mg/ml |
| Storage buffer: | Whole serum |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
Robinson et al. 2002. J Biol Chem. 277(5):3658-65. PMID: 11723110. The S100 family heterodimer, MRP-8/14, binds with high affinity to heparin and heparan sulfate glycosaminoglycans on endothelial cells. Robinson et al. 2000. Biochem Biophys Res Commun. 275(3):865-70. PMID: 10973813. A comparison of human S100A12 with MRP-14 (S100A9). |
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