Together with heterodimeric partner S100a9, S100a8 is a major biomarker of inflammation both in released form in serum and through increased expression in epithelial tissue and in many tumour models.
| Inventor | Institute |
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| Nancy Hogg | Cancer Research UK, London Research Institute: Lincoln's Inn Fields |
| SKU: | 153164 |
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| Product description: | Together with heterodimeric partner S100a9, S100a8 is a major biomarker of inflammation both in released form in serum and through increased expression in epithelial tissue and in many tumour models. |
| Alternate name: | mMRP-8, calgranulin A |
| Conjugation: | Unconjugated |
| Molecular weight: | 8 kDa |
| Immunogen: | Synthesised full length mouse S100a8 |
| Cat. #: | 153164 |
|---|---|
| Provenance and Ownership: | The Anti-S100a8 [NH9] is owned by Cancer Research UK. CancerTools supplies the Anti-S100a8 [NH9] under licence from Cancer Research UK and is the authorised source for its distribution. Sourcing Anti-S100a8 [NH9] directly from the IP owner ensures authenticity, provenance and compliance with all applicable licensing and research use requirements. |
| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Cancer; Cell signaling and signal transduction; Immunology; Neurobiology |
| Application: | WB |
| Target: | S100a8 |
| Reactivity: | Mouse |
| Clone: | NH9 |
| Host: | Rabbit |
| Class: | Polyclonal |
| Target background: | Together with heterodimeric partner S100a9, S100a8 is a major biomarker of inflammation both in released form in serum and through increased expression in epithelial tissue and in many tumour models. |
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| Format: | Liquid |
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| Storage buffer: | Whole serum |
| Storage conditions: | -80° C |
| Shipping conditions: | Dry ice |
| References: |
Baker et al. 2011. Dev Dyn. 240(9):2194-203. PMID: 22016186. Distinct roles for S100a8 in early embryo development and in the maternal deciduum. Hobbs et al. 2003. Mol Cell Biol. 23(7):2564-76. PMID: 12640137. Myeloid cell function in MRP-14 (S100A9) null mice. |
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