During genetic recombination and post replication repair of DNA damage, RuvA and RuvB (a helicase) act in a complex to promote branch migration of Holliday junctions.
| Inventor | Institute |
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| Stephen West | Cancer Research UK, London Research Institute: Clare Hall Laboratories |
| SKU: | 151330 |
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| Product description: | During genetic recombination and post replication repair of DNA damage, RuvA and RuvB (a helicase) act in a complex to promote branch migration of Holliday junctions. |
| Conjugation: | Unconjugated |
| Immunogen: | RuvB (E-coli) purified protein |
| Cat. #: | 151330 |
|---|---|
| Provenance and Ownership: | The Anti-RuvB [SWE4] is owned by Cancer Research UK. CancerTools supplies the Anti-RuvB [SWE4] under licence from Cancer Research UK and is the authorised source for its distribution. Sourcing Anti-RuvB [SWE4] directly from the IP owner ensures authenticity, provenance and compliance with all applicable licensing and research use requirements. |
| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Genetics |
| Application: | IP ; WB |
| Target: | RuvB |
| Reactivity: | E.coli |
| Clone: | SWE4 |
| Host: | Rabbit |
| Class: | Polyclonal |
| Target background: | During genetic recombination and post replication repair of DNA damage, RuvA and RuvB (a helicase) act in a complex to promote branch migration of Holliday junctions. |
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| Format: | Liquid |
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| Concentration: | 0.9-1.1 mg/ml |
| Storage buffer: | Serum |
| Storage conditions: | -80° C |
| Shipping conditions: | Dry ice |
| References: |
Davies et al. 1998. Curr Biol. 8(12):725-7. PMID: 9637927. Formation of RuvABC-Holliday junction complexes in vitro. Eggleston et al. 1997. Cell. 89(4):607-17. PMID: 9160752. In vitro reconstitution of the late steps of genetic recombination in E. coli. |
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