RAD51C is a RAD51 paralogue. Rad51 is a eukaryotic homologue of E. coli RecA, a recombinase, and a component of the homologous recombination DNA repair pathway.
| Inventor | Institute |
|---|---|
| Madalena Tarsounas | Cancer Research UK, London Research Institute: Clare Hall Laboratories |
| SKU: | 151457 |
|---|---|
| Product description: | RAD51C is a RAD51 paralogue. Rad51 is a eukaryotic homologue of E. coli RecA, a recombinase, and a component of the homologous recombination DNA repair pathway. RAD51 forms a nucleoprotein filament (through binding RAD52 and single stranded DNA that are exposed following double strand breaks) that initiates recombination. RAD51C is also a component for the homologous recombination pathway of DNA repair. |
| Conjugation: | Unconjugated |
| Immunogen: | Mouse n-terminal RAD51C peptide . |
| Cat. #: | 151457 |
|---|---|
| Provenance and Ownership: | The Anti-Rad51C [MTA36] is owned by Cancer Research UK. CancerTools supplies the Anti-Rad51C [MTA36] under licence from Cancer Research UK and is the authorised source for its distribution. Sourcing Anti-Rad51C [MTA36] directly from the IP owner ensures authenticity, provenance and compliance with all applicable licensing and research use requirements. |
| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Genetics |
| Application: | IP ; WB |
| Target: | Rad51C |
| Reactivity: | Mouse |
| Clone: | MTA36 |
| Host: | Rabbit |
| Class: | Polyclonal |
| Target background: | RAD51C is a RAD51 paralogue. Rad51 is a eukaryotic homologue of E. coli RecA, a recombinase, and a component of the homologous recombination DNA repair pathway. RAD51 forms a nucleoprotein filament (through binding RAD52 and single stranded DNA that are exposed following double strand breaks) that initiates recombination. RAD51C is also a component for the homologous recombination pathway of DNA repair. |
|---|
| Format: | Liquid |
|---|---|
| Concentration: | 0.9-1.1 mg/ml |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
Badie et al. 2009. J Cell Biol. 185(4):587-600. PMID: 19451272. RAD51C facilitates checkpoint signaling by promoting CHK2 phosphorylation. |
|---|
| Cat. # | Tool Name | |||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 151031 | Anti-RuvA [RuvA 12C6] |
Key Info
Anti-RuvA [RuvA 12C6]
|
View Tool | |||||||||||||||||||
| 151023 | Anti-IL12 [1-1D5] |
Key Info
Anti-IL12 [1-1D5]
|
View Tool | |||||||||||||||||||
| 151027 | Anti-HSVICP8 [10A3] |
Key Info
Anti-HSVICP8 [10A3]
|
View Tool | |||||||||||||||||||
| 151037 | Anti-Cdk1 [17 (A17)] |
Key Info
Anti-Cdk1 [17 (A17)]
|
View Tool | |||||||||||||||||||
| 151040 | Anti-Integrins aL, aX, aMb2 [24] |
Key Info
Anti-Integrins aL, aX, aMb2 [24]
|
View Tool | |||||||||||||||||||
Please note we may take up to three days to respond to your enquiry.
CancerTools.org uses the contact information provided to respond to you about our research tools and service. For more information please review our privacy policy.