PyC allows the detection and isolation of all three viral T antigens.
| Inventor | Institute |
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| Stephen Dilworth | Cancer Research UK, London Research Institute: Lincoln's Inn Fields |
| SKU: | 151188 |
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| Product description: | PyC allows the detection and isolation of all three viral T antigens. |
| Conjugation: | Unconjugated |
| Isotype: | IgG2b |
| Molecular weight: | 100/55/23 kDa |
| Immunogen: | Polyoma virus-transformed Wistar rat fibroblast cell line Py REWA5/T1A1. |
| Myeloma used: | P3/NS1/1-Ag4.1 |
| Cat. #: | 151188 |
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| Provenance and Ownership: | The Anti-PyLT [PyC] is owned by Cancer Research UK. CancerTools supplies the Anti-PyLT [PyC] under licence from Cancer Research UK and is the authorised source for its distribution. Sourcing Anti-PyLT [PyC] directly from the IP owner ensures authenticity, provenance and compliance with all applicable licensing and research use requirements. |
| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Microbiology |
| Application: | IF ; IP ; WB |
| Target: | Polyoma virus Early antigens |
| Reactivity: | Virus |
| Clone: | PyC |
| Host: | Rat |
| Class: | Monoclonal |
| Target background: | The mouse polyoma virus (Py) is an oncogenic virus, which encodes for three early proteins, large, middle and small T (tumour) antigen. |
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| Format: | Liquid |
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| Concentration: | 0.9-1.1 mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
Dilworth et al. 1982. EMBO J. 1(11):1319-28. PMID: 6327264. Dilworth et al. 1982. Proc Natl Acad Sci U S A. 79(4):1059-63. PMID: 6175960. Monoclonal antibodies against polyoma virus tumor antigens. Protein kinase activities associated with distinct antigenic forms of polyoma virus middle T-antigen. |
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