Protein argonaute-2 plays a role in RNA interference and contains a PAZ and PIWI domain. Ago2, in humans, is responsible for the endonuclease cleavage of targeted mRNA and interacts with GW182 (mRNA binding protein) which is a marker for cytiplasmic foci called GW bodies. This monoclonal antibody may be useful in detecting functional microRNAs.
| Institute |
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| University of Florida |
| SKU: | 158412 |
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| Product description: | Protein argonaute-2 plays a role in RNA interference and contains a PAZ and PIWI domain. Ago2, in humans, is responsible for the endonuclease cleavage of targeted mRNA and interacts with GW182 (mRNA binding protein) which is a marker for cytiplasmic foci called GW bodies. This monoclonal antibody may be useful in detecting functional microRNAs. |
| Alternate name: | AGO2; EIF2C2 |
| Conjugation: | Unconjugated |
| Isotype: | IgA kappa |
| Immunogen: | Pristane-primed and recombinant full length human protein |
| Cat. #: | 158412 |
|---|---|
| Unit size: | 100 ug |
| Research Fields: | Genetics |
| Application: | WB ; IF ; IP |
| Target: | Protein argonaute-2 |
| Reactivity: | Human ; Rat ; Mouse |
| Host: | Mouse |
| Class: | Monoclonal |
| Target background: | Protein argonaute-2 plays a role in RNA interference and contains a PAZ and PIWI domain. Ago2, in humans, is responsible for the endonuclease cleavage of targeted mRNA and interacts with GW182 (mRNA binding protein) which is a marker for cytiplasmic foci called GW bodies. This monoclonal antibody may be useful in detecting functional microRNAs. |
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| Format: | Liquid |
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| Shipping conditions: | Dry ice |
| References: |
Ikeda et al. 2006. J Immunol Methods. 317(1-2):38-44. PMID: 17054975. |
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