Anti-PIWIL3 [Z83]

PIWIL3 may play a role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity.

Contributors

Inventor Institute
Ayham Alnabulsi Vertebrate Antibodies Limited
SKU: 153471
Product description: PIWIL3 may play a role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. PIWIL3 acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. PIWIL3 directly binds piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a D…
Alternate name: Anti-PIWIL3 antibody, HIWI3 antibody, Piwi like 3 antibody, PIWL3_HUMAN antibody
Conjugation: Unconjugated
Isotype: IgG
Immunogen: Ovalbumin-conjugated synthetic peptide PNRSLSTRLFYL- peptide immunogen is identical in primates
Myeloma used: P3X63Ag8.653
Cat. #: 153471
Tool sub type: Primary antibody
Unit size: 100 ug
Cancer types: Ovarian cancer
Research Fields: Developmental biology; Genetics; Stem cell biology
Application: ELISA ; IHC ; WB
Target: Piwi Like RNA-Mediated Gene Silencing 3
Reactivity: Human
Clone: Z83
Host: Mouse
Class: Monoclonal
Target background: PIWIL3 may play a role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. PIWIL3 acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. PIWIL3 directly binds piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a D…
Format: Liquid
Shipping conditions: Dry ice

Images

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Western blot showing detection of PIWIL3 in (A) Jurkat and (B) Hela cell lysates using Anti-PIWIL3 [Z83]. Antibody was used at 1 in 2 dilution.

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