Anti-Pinin [Pinin]

Pinin has also been reported to have a role in RNA processing and transcriptional regulation and is part of the SNARP complex. Together with SNIP1 and other proteins Pinin has a role in regulation of proliferation and cancer.

Contributors

Inventor Institute
Neil Perkins University of Dundee
SKU: 151617
Product description: Pinin is a cell adhesion-associated and nuclear protein that has been shown to localize in the vicinity of intermediate filament (IF) convergence upon the cytoplasmic face of the desmosomal plaque as well as in the nucleus. Some data suggest that pinin may play a role in epithelial cell adhesion and the IF complex through a direct interaction with the keratin filaments. Pinin has also been reported to have a role in RNA processing and transcriptional regulation and is part of the SNARP complex. Together with SNIP1 and other proteins Pinin has a role in regulation of proliferation and cancer.
Conjugation: Unconjugated
Immunogen: Recombinant his-tagged protein
Cat. #: 151617
Tool sub type: Primary antibody
Unit size: 100 ug
Research Fields: Cancer; Genetics
Application: ELISA ; IHC ; IF ; IP ; WB
Target: Pinin
Reactivity: Human
Clone: Pinin
Host: Rabbit
Class: Polyclonal
Target background: Pinin is a cell adhesion-associated and nuclear protein that has been shown to localize in the vicinity of intermediate filament (IF) convergence upon the cytoplasmic face of the desmosomal plaque as well as in the nucleus. Some data suggest that pinin may play a role in epithelial cell adhesion and the IF complex through a direct interaction with the keratin filaments. Pinin has also been reported to have a role in RNA processing and transcriptional regulation and is part of the SNARP complex. Together with SNIP1 and other proteins Pinin has a role in regulation of proliferation and cancer.
Format: Liquid
Concentration: 0.9-1.1 mg/ml
Storage conditions: -15° C to -25° C
Shipping conditions: Dry ice
References:

Carvalho et al. 2017. J Cell Sci. 130(9):1519-1531. PMID: 28302904.

Bracken et al. 2008. Cancer Res. 68(18):7621-8. PMID: 18794151.

Bracken et al. 2008. Cancer Res. 68(18):7621-8. PMID: 18794151.

Regulation of cyclin D1 RNA stability by SNIP1.

Images

View Gallery

Tool enquiry

Please ensure you use your organisation email address rather than personal where possible, as this helps us locate your organisation in our system faster.

Please note we may take up to three days to respond to your enquiry.

CancerTools.org uses the contact information provided to respond to you about our research tools and service. For more information please review our privacy policy.