Transforming acidic coiled coil (TACC) proteins stabilize MTs during mitosis by recruiting Minispindles (Msps)/XMAP215 proteins to centrosomes. Drosophila melanogaster TACC (D-TACC) is phosphorylated on Ser863 exclusively at centrosomes during mitosis in an Aurora A–dependent manner.
| Inventor | Institute |
|---|---|
| Jordan Raff | University of Cambridge |
| SKU: | 151800 |
|---|---|
| Product description: | Transforming acidic coiled coil (TACC) proteins stabilize MTs during mitosis by recruiting Minispindles (Msps)/XMAP215 proteins to centrosomes. Drosophila melanogaster TACC (D-TACC) is phosphorylated on Ser863 exclusively at centrosomes during mitosis in an Aurora AÄËĂÂĂÂdependent manner. |
| Conjugation: | Unconjugated |
| Immunogen: | synthetic peptide sequence |
| Cat. #: | 151800 |
|---|---|
| Provenance and Ownership: | The Anti-Phospho D-TACC [MA8] is owned by Cancer Research UK. CancerTools supplies the Anti-Phospho D-TACC [MA8] under licence from Cancer Research UK and is the authorised source for its distribution. Sourcing Anti-Phospho D-TACC [MA8] directly from the IP owner ensures authenticity, provenance and compliance with all applicable licensing and research use requirements. |
| Unit size: | 100 ug |
| Research Fields: | Cell biology |
| Application: | IF ; WB |
| Target: | Phospho drosophila transforming acidic coiled coil (TACC) |
| Reactivity: | Drosophila |
| Clone: | MA8 |
| Host: | Rabbit |
| Class: | Polyclonal |
| Target background: | Transforming acidic coiled coil (TACC) proteins stabilize MTs during mitosis by recruiting Minispindles (Msps)/XMAP215 proteins to centrosomes. Drosophila melanogaster TACC (D-TACC) is phosphorylated on Ser863 exclusively at centrosomes during mitosis in an Aurora AÄËĂÂĂÂdependent manner. |
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| Format: | Liquid |
|---|---|
| Shipping conditions: | Dry ice |
| References: |
Raff et al. 2005.J Cell Biol. 170:1039-46. PMID: 16186253 |
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