Antibody for PES1, also known as Pescadillo Ribosomal Biogenesis Factor 1, a protein coding gene. PES1 encodes a nuclear protein containing a breast cancer associated gene 1 (BRCA1) C-terminal interaction domain. The encoded protein interacts with BOP1 and WDR12 to form the PeBoW complex, which plays a critical role in cell proliferation via pre-rRNA processing […]
| Institute |
|---|
| Helmholtz Munich Core Facility Monoclonal Antibodies |
| Cat. #: | 162379 |
|---|---|
| Tool sub type: | Primary antibody |
| Cancer types: | Head and neck cancer;Breast cancer;Liver cancer |
| Research Fields: | Cancer;Cell biology |
| Application: | WB, IP |
| Target: | Human Pescadillo Ribosomal Biogenesis Factor 1 (Pes1) |
| Reactivity: | Human |
| Clone: | PES1 8E9 |
| Host: | Rat |
| Class: | Monoclonal |
| Primary citation: | Holzel et al. 2005. J. Cell Biol. 170: 367-378. PMID: 16043514 |
| Alternate name: | Anti human Pescadillo Ribosomal Biogenesis Factor 1 (Pes1) monoclonal antibody (clone PES1 8E9) |
|---|---|
| Product description: | Antibody for PES1, also known as Pescadillo Ribosomal Biogenesis Factor 1, a protein coding gene. PES1 encodes a nuclear protein containing a breast cancer associated gene 1 (BRCA1) C-terminal interaction domain. The encoded protein interacts with BOP1 and WDR12 to form the PeBoW complex, which plays a critical role in cell proliferation via pre-rRNA processing and 60S ribosomal subunit maturation. PES1 has been implicated in multiple cancer types including breast cancer, head and neck cancer, liver cancer and others. |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Immunogen: | Ovalbumin coupled to AGSEKEEEARLAALEEQRMEGK peptide |
| Target background: | Pescadillo Ribosomal Biogenesis Factor 1encodes a nuclear protein that contains a breast cancer associated gene 1 (BRCA1) C-terminal interaction domain. The encoded protein interacts with BOP1 and WDR12 to form the PeBoW complex, which plays a critical role in cell proliferation via pre-rRNA processing and 60S ribosomal subunit maturation. Expression of this gene may play an important role in breast cancer proliferation and tumorigenicity. |
|---|
| References: |
Holzel, M. et al. J. Cell Biol. (2005) 170,367-378, PMID: 16043514 |
|---|
| Cat. # | Tool Name | |||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 151016 | Anti-CyclinA [E72.1] |
Key Info
Anti-CyclinA [E72.1]
|
View Tool | |||||||||||||||||||
| 151025 | Anti-Vascular endothelium [10] |
Key Info
Anti-Vascular endothelium [10]
|
View Tool | |||||||||||||||||||
| 151037 | Anti-Cdk1 [17 (A17)] |
Key Info
Anti-Cdk1 [17 (A17)]
|
View Tool | |||||||||||||||||||
| 151017 | Anti-MBP [R29.6] |
Key Info
Anti-MBP [R29.6]
|
View Tool | |||||||||||||||||||
| 151035 | Anti-CD8 [14] mAb |
Key Info
Anti-CD8 [14] mAb
|
View Tool | |||||||||||||||||||
Please note we may take up to three days to respond to your enquiry.
CancerTools.org uses the contact information provided to respond to you about our research tools and service. For more information please review our privacy policy.