Anti-p53 [V5P4H6*B3]

p53 acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an […]

Contributors

Inventor Institute
Ayham Alnabulsi Vertebrate Antibodies Limited
Cat. #: 152613
Tool sub type: Primary antibody
Unit size: 100 ug
Research Fields: Apoptosis and autophagy;Cancer;Cell biology;Genetics
Application: ELISA ; IHC ; WB
Target: p53
Reactivity: Zebrafish
Clone: V5P4H6*B3
Host: Mouse
Class: Monoclonal
Product description: p53 acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of B…
Conjugation: Unconjugated
Isotype: IgG1 kappa
Immunogen: Ovalbumin-conjugated synthetic peptide KLMVKDEGRS (C-terminal sequence)
Target background: p53 acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of B…
Format: Liquid
Concentration: 1 mg/ml
Storage buffer: PBS with 0.02% azide
Storage conditions: -20° C
Shipping conditions: Dry ice

Images

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Immunohistochemistry using anti-p53 [V5P4H6*B3] on a Zebrafish embryo.

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