Anti-ORC1 [ORC1 7F6/1]
Contributors
| Institute |
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| Cancer Research UK, London Research Institute: Clare Hall Laboratories |
| SKU: | 151191 |
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| Product description: | Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Molecular weight: | 45-97 kDa |
| Immunogen: | Bacterially expressed Human ORC1 |
| Myeloma used: | Sp2/0-Ag14 |
| Cat. #: | 151191 |
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| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Genetics |
| Application: | IP ; ChIP ; ELISA ; IHC ; IP ; WB ; ChIP-seq |
| Target: | ORC1 |
| Reactivity: | Human |
| Clone: | ORC1 7F6/1 |
| Host: | Mouse |
| Class: | Monoclonal |
| Target background: | Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. |
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| Format: | Liquid |
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| Concentration: | 0.76 mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
Lu et al. 2016. Biol Open. 5(10):1449-1460. PMID: 27744293. Beck et al. 2012. Genes Dev. 26(23):2580-9. PMID: 23152447. Salsi et al. 2009. Mol Cell Biol. 29(21):5775-88. PMID: 19703996. Burke et al. 2001. J Biol Chem. 276(18):15397-408. PMID: 11278932. |
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Adapted from Lu et al. Biology Open (2016) 5; 1449-1460 doi
