Anti-O-GlcNAc (CTD110.6)

Contributors

Inventor Institute
Gerald Hart Johns Hopkins University
SKU: 153987
Product description: The ?-O-linked N-acetylglucosamine (O-GlcNAc) antibody recognizes glycosylation, a post-translational modification, which occurs on serine and threonine residues of proteins in the nuclear and cytoplasmic compartments. This type of glycosylation results in a single moiety and not a complex branched structure. The O-GlcNAc antibody does not cross react with ?-linked Ser/Thr-O-GlcNAc, ?-linked Ser-O-linked N-acetylgalactosamine or N-linked oligosaccharides on ovalbumin and immunoglobulin G.
Conjugation: Unconjugated
Isotype: IgM
Immunogen: Synthetic glycopeptide (YSPTS(O-GlcNAc)PSK)
Cat. #: 153987
Tool sub type: Primary antibody
Unit size: 100 ug
Research Fields: Biochemistry; Cell signaling and signal transduction
Application: ELISA ; IHC ; IP ; WB
Target: ?-O-linked N-acetylglucosamine (O-GlcNAc) in ?-O-glycosidic linkage to both serine and threonine and does not cross react with a-linked Ser/Thr-O-GlcNAc, a-linked Ser-O-linked N-acetylgalactosamine or N-linked oligosaccharides on ovalbumin and immunoglobulin G.
Reactivity: Human ; Mouse ; Primate ; Rat ; All
Host: Mouse
Class: Monoclonal
Target background: The ?-O-linked N-acetylglucosamine (O-GlcNAc) antibody recognizes glycosylation, a post-translational modification, which occurs on serine and threonine residues of proteins in the nuclear and cytoplasmic compartments. This type of glycosylation results in a single moiety and not a complex branched structure. The O-GlcNAc antibody does not cross react with a-linked Ser/Thr-O-GlcNAc, a-linked Ser-O-linked N-acetylgalactosamine or N-linked oligosaccharides on ovalbumin and immunoglobulin G.
Format: Liquid
Storage conditions: -20° C
Shipping conditions: Dry ice
References:

Comer et al. 2001. Anal Biochem. 293(2):169-77. PMID: 11399029.

Characterization of a mouse monoclonal antibody specific for O-linked N-acetylglucosamine.

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