| Institute |
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| A*STAR Accelerate Technologies Pte Ltd |
| SKU: | 152664 |
|---|---|
| Product description: | Hepatitis C virus (HCV) encodes a polyprotein that is cleaved into at least 10 viral proteins namely E1, E2, core, p7, NS2, NS3, NS4A, NS4B, NS5A, and NS5B. Non-structural 5B protein (NS5B) is HCVÄËĂÂĂÂs RNA dependant RNA polymerase and is critical for viral replication. |
| Conjugation: | Unconjugated |
| Isotype: | IgG2a |
| Immunogen: | GST-NS5B (residues 1-346) fusion protein of a HCV genotype 2a strain |
| Myeloma used: | Sp2/0-Ag14 |
| Cat. #: | 152664 |
|---|---|
| Unit size: | 100 ug |
| Research Fields: | Microbiology |
| Application: | IF ; WB |
| Target: | Hepatitis C virus non-structural protein 5B |
| Reactivity: | Virus |
| Clone: | 1A4 |
| Host: | Mouse |
| Class: | Monoclonal |
| Target background: | Hepatitis C virus (HCV) encodes a polyprotein that is cleaved into at least 10 viral proteins namely E1, E2, core, p7, NS2, NS3, NS4A, NS4B, NS5A, and NS5B. Non-structural 5B protein (NS5B) is HCVÄËĂÂĂÂs RNA dependant RNA polymerase and is critical for viral replication. |
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| Format: | Liquid |
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| Concentration: | 0.9-1.1mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
Aweya et al. 2015. Virology. 474:41-51. PMID: 25463603. NS5B induces up-regulation of the BH3-only protein, BIK, essential for the hepatitis C virus RNA replication and viral release. |
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