Anti-Nampt [14A5]

Nicotinamide phosphoribosyltransferase (NAMPT) is a member of the NAPRTase family. Its primary role is to catalyze the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD. NAMPT is localized in the cytoplasm and expressed in large amounts in bone marrow, liver tissue, and muscle tissues. NAMPT inhibits neutrophil apoptosis in experimental inflammation and clinical sepsis.

Contributors

Inventor Institute
Anthony Rongvaux, Fabienne Andris Free University of Brussels
SKU: 152144
Product description: Nicotinamide phosphoribosyltransferase (NAMPT) is a member of the NAPRTase family. Its primary role is to catalyze the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD.
Conjugation: Unconjugated
Isotype: IgG2a kappa
Molecular weight: 52 kDa
Immunogen: Recombinant mouse Nampt
Cat. #: 152144
Tool sub type: Primary antibody
Research Fields: Cancer; Cell signaling and signal transduction; Immunology; Metabolism; Neurobiology; Tissue-specific biology
Application: ELISA ; IHC ; IP ; WB ; enzymatic activity inhibition
Target: Nicotinamide phosphoribosyl transferase (NAMPT)
Reactivity: Human ; Mouse
Clone: 14A5
Host: Rat
Class: Monoclonal
Primary citation: Rongvaux et al. 2002. Eur J Immunol. 32(11):3225-34. PMID: 12555668.
Target background: Nicotinamide phosphoribosyltransferase (NAMPT) is a member of the NAPRTase family. Its primary role is to catalyze the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD.
Shipping conditions: Dry ice
References:

Rongvaux et al. 2002. Eur J Immunol. 32(11):3225-34. PMID: 12555668.

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