Clone Myo 2/1A has been shown to have the reverse effect, up-regulate myogenesis and down-regulate adipogenesis.
| Institute |
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| BioServ UK Ltd |
| Cat. #: | 153655 |
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| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Cell signaling and signal transduction |
| Application: | WB |
| Target: | Myostatin |
| Reactivity: | Human |
| Clone: | Myo2/1A |
| Host: | Mouse |
| Class: | Monoclonal |
| Alternate name: | Growth/differentiation factor 8, GDF-8, myostatin, GDF8, MSTN |
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| Product description: | Myostatin is a well-characterized negative regulator of skeletal muscle and can inhibit myogenesis and stimulate adipogenesis. Clone Myo 2/1A has been shown to have the reverse effect, up-regulate myogenesis and down-regulate adipogenesis. |
| Conjugation: | Unconjugated |
| Molecular weight: | 52 kDa |
| Immunogen: | Recognizes the 113 amino acid carboxy-terminal fragment of Myostatin protein |
| Myeloma used: | Sp2/0-Ag14 |
| Target background: | Myostatin is a well-characterized negative regulator of skeletal muscle and can inhibit myogenesis and stimulate adipogenesis. Clone Myo 2/1A has been shown to have the reverse effect, up-regulate myogenesis and down-regulate adipogenesis. |
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| Format: | Liquid |
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| Shipping conditions: | Dry ice |
| References: |
Artaza et al. 2005. Endocrinology. 146(8):3547-57. PMID: 15878958. Myostatin inhibits myogenesis and promotes adipogenesis in C3H 10T(1/2) mesenchymal multipotent cells. |
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