Anti-Myelin Basic Protein (region 36-50) [MBP14]

MBP Clone 14 recognizes an epitope in the 36-50 region of MBP, useful in clinical diagnosis to detect MBP levels or myelination in human MBP.

Contributors

Institute
BioServ UK Ltd
SKU: 153642
Product description: Myelin Basic Protein (MBP) is involved in the process of myelination of nerves in the nervous system. MBP Clone 14 recognizes an epitope in the 36-50 region of MBP, useful in clinical diagnosis to detect MBP levels or myelination in human MBP.
Alternate name: Myelin basic protein, MBP, 2 kDa microtubule-stabilizing protein, Myelin A1 protein
Conjugation: Unconjugated
Isotype: IgG2b
Molecular weight: 13-21 kDa
Immunogen: Reacts with human MBP, recognizing epitopes in the 36-50 amino acid region (GILDSIGRFFGGDRG)
Myeloma used: NS0
Cat. #: 153642
Tool sub type: Primary antibody
Unit size: 100 ug
Cancer types: Brain cancer
Research Fields: Cell biology; Immunology; Neurobiology
Application: ELISA ; IHC ; IF ; WB
Target: Myelin Basic Protein (region 36-50)
Reactivity: Bovine ; Chicken ; Horse ; Human
Clone: MBP14
Host: Rat
Class: Monoclonal
Target background: Myelin Basic Protein (MBP) is involved in the process of myelination of nerves in the nervous system. MBP Clone 14 recognizes an epitope in the 36-50 region of MBP, useful in clinical diagnosis to detect MBP levels or myelination in human MBP.
Format: Liquid
Shipping conditions: Dry ice
References:

Friess et al. 2016. Cell Calcium. 60(5):322-330. PMID: 27417499.

Intracellular ion signaling influences myelin basic protein synthesis in oligodendrocyte precursor cells.

Jackson et al. 2004. Eur J Neurosci. 20(9):2267-75. PMID: 15525268.

Cannabinoid-mediated neuroprotection following interferon-gamma treatment in a three-dimensional mouse brain aggregate cell culture.

Matsuo et al. 1997. Am J Pathol. 150(4):1253-66. PMID: 9094982.

Unmasking of an unusual myelin basic protein epitop…

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Clone MBP 14 used to detect myelinated structures in MS plaques by IHC-P. ...clone 14 (B); and clone 2 (C) recognized all myelinated structures in control brains; whereas no immunoreactivity was detected by EP antiserum. Source

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