Anti-MMP2 [4D3]

Mutations of MMP2 are associated with Torg-Winchester syndrome.

Contributors

Inventor Institute
Ayham Alnabulsi Vertebrate Antibodies Limited
SKU: 151619
Product description: MMP2 degrades type IV collagen and plays an important role in menstrual break down, regulation of vascularization, angiogenesis, and inflammatory response. Mutations of MMP2 are associated with Torg-Winchester syndrome.
Conjugation: Unconjugated
Isotype: IgG1
Immunogen: Ovalbumin-conjugated synthetic peptide; TSLGLPPDVQRVD
Myeloma used: P3X63Ag8.653
Cat. #: 151619
Tool sub type: Primary antibody
Unit size: 100 ug
Research Fields: Cancer;Cell biology;Genetics;Metabolism;Tissue-specific biology
Application: ELISA ; IHC ; IF ; IP ; WB
Target: Human matrix metalloproteinase 2 (MMP-2)
Reactivity: Human
Clone: 4D3
Host: Mouse
Class: Monoclonal
Target background: MMP2 degrades type IV collagen and plays an important role in menstrual break down, regulation of vascularization, angiogenesis, and inflammatory response. Mutations of MMP2 are associated with Torg-Winchester syndrome.
Format: Liquid
Storage buffer: PBS with 0.02% azide
Storage conditions: -80° C
Shipping conditions: Dry ice
References:

Jeffery et al. 2009. Histopathology. 54(7):820-8. PMID: 19635101.

The matrix metalloproteinase/tissue inhibitor of matrix metalloproteinase profile in colorectal polyp cancers.

Lyall et al. 2006. Clin Cancer Res. 12(4):1184-91. PMID: 16489072.

Profiling markers of prognosis in colorectal cancer.

Curran et al. 2004. Clin Cancer Res. 10(24):8229-34. PMID: 15623598.

Matrix metalloproteinase/tissue inhibitors of matrix metalloproteinase phenotype identifies poor prognosis colorectal cancers.

Murray et al. 1998. Gut. 43(6):791-7. PMID: 9824606.

Matrix metalloproteinases and their inhibitors in gastric cancer.

Murray et al. 1998. J Pathol. 185(3):256-61. PMID: 9771478.

Matrix metalloproteinase-1 is associated with poor prognosis in oesophageal cancer.

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