Anti-Metapneumovirus Fusion Protein [hMPV24]

Monoclonal antibody which can identify human metapneumovirus via immunofluorescent staining and does not cross react to other cell cultures

Contributors

Inventor Institute
Geoff Toms Newcastle University
SKU: 151640
Product description: Monoclonal antibody which can identify human metapneumovirus via immunofluorescent staining and does not cross react to other cell cultures Background and Research Application Anti-hMPV monoclonal antibody which can identify and locate the fusion glycoprotein of human metapneumovirus (hMPV) of both types A and B, within a sample. hMPV is a negative single stranded RNA virus of the paramyxoviridae family and can cause upper and lower respiratory tract infections. Discovered in 2001, there appear to be 4 lineages of the hMPV virus, stemming from sub-groups A and B.Anti-hMPV24 can recognise the fusion protein of all 4 lineages(A1,A2, B1 and B2). Anti-hMPV24 be also used in conjunction with other hMPV antibody clones to detect all strains of the virus. Anti-hMPV24 was created to diagnose hMPV infection in respiratory specimens via immunofluorescence staining with optimal staining of clinical samples with low backgrounds on uninfected specimens.
Conjugation: Unconjugated
Isotype: IgG2a kappa
Immunogen: Human MPV strain NCL-145
Myeloma used: P3/NS1/1-Ag4.1
Cat. #: 151640
Unit size: 100 ug
Research Fields: Microbiology
Application: IHC; IF ; WB
Target: Metapneumovirus Fusion Protein
Reactivity: Virus
Clone: hMPV24
Host: Mouse
Class: Monoclonal
Target background: Monoclonal antibody which can identify human metapneumovirus via immunofluorescent staining and does not cross react to other cell cultures Background and Research Application Anti-hMPV monoclonal antibody which can identify and locate the fusion glycoprotein of human metapneumovirus (hMPV) of both types A and B, within a sample. hMPV is a negative single stranded RNA virus of the paramyxoviridae family and can cause upper and lower respiratory tract infections. Discovered in 2001, there appear to be 4 lineages of the hMPV virus, stemming from sub-groups A and B.Anti-hMPV24 can recognise the fusion protein of all 4 lineages(A1,A2, B1 and B2). Anti-hMPV24 be also used in conjunction with other hMPV antibody clones to detect all strains of the virus. Anti-hMPV24 was created to diagnose hMPV infection in respiratory specimens via immunofluorescence staining with optimal staining of clinical samples with low backgrounds on uninfected specimens.
Format: Liquid
Concentration: 1 mg/ml
Storage buffer: PBS with 0.02% sodium azide
Storage conditions: -15° C to -25° C
Shipping conditions: Dry ice
References:

Fenwick F. et al. 2007. J Clin Virol. 40:193-6. PMID: 17869169

Tedcastle AB. et al. 2012. J Med Virol. 84(7):1061-70.PMID: 22585723

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Adapted from El Najjar et al. 2016. PLoS Pathog; 12(9)

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