Anti-Melanoma Associated Antigen 100 (Gp100) [Beteb]

Release of the soluble form, ME20-S, could protect tumour cells from antibody mediated immunity.

Contributors

Institute
Netherlands Cancer Institute
SKU: 154782
Product description: Gp100 plays a central role in the biogenesis of melanosomes. Involved in the maturation of melanosomes from stage I to II. The transition from stage I melanosomes to stage II melanosomes involves an elongation of the vesicle, and the appearance within of distinct fibrillar structures. Release of the soluble form, ME20-S, could protect tumour cells from antibody mediated immunity.
Conjugation: Unconjugated
Isotype: IgG2b
Molecular weight: 70 kDa
Immunogen: Purified membranes of a human melanoma lymph node metastasis
Myeloma used: Sp2/0-Ag14
Cat. #: 154782
Tool sub type: Primary antibody
Unit size: 100 ug
Research Fields: Cancer; Cell biology
Application: IHC
Target: Melanoma Associated Antigen 100
Reactivity: Human
Host: Mouse
Class: Monoclonal
Target background: Gp100 plays a central role in the biogenesis of melanosomes. Involved in the maturation of melanosomes from stage I to II. The transition from stage I melanosomes to stage II melanosomes involves an elongation of the vesicle, and the appearance within of distinct fibrillar structures. Release of the soluble form, ME20-S, could protect tumour cells from antibody mediated immunity.
Format: Liquid
Concentration: 0.9-1.1 mg/ml
Storage buffer: PBS with 0.02% azide
Storage conditions: -15° C to -25° C
Shipping conditions: Dry ice
References:

Vennegoor et al. 1988. Am J Pathol. 130(1):179-92. PMID: 3276209.

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